The Research Infrastructures work programme supports activities to consolidate, evolve, open, integrate and interconnect a world leading ecosystem of research services for researchers in Europe, encompassing both national and pan-European infrastructures. The aim is to cover the continuum of needs from the creation of fundamental knowledge to technology development and innovation, while supporting open science.

The Research Infrastructures work programme is structured around the following four destinations:

• INFRADEV - Consolidation and evolution of the European Research Infrastructure landscape, to develop an integrated European ecosystem of research infrastructures, including single-sited facilities, distributed facilities and networks of facilities providing joint services.
• INFRAEOSC - Enabling an operational, open and FAIR EOSC ecosystem, to contribute to a web of FAIR (Findable, Accessible, Interoperable, Reusable) research data and provide a trusted and secure federated system of research data and services (EOSC Federation) for researchers in the EU and Associated Countries to store, share, process and reuse within and across disciplines and borders FAIR research outputs and tools for research, innovation and educational purposes.
• INFRASERV - Research infrastructures services to support health research, accelerate the green transition and the digital transformation, and advance frontier knowledge the access to RIs, to support transnational access to state-of-the-art facilities for researchers, relevant for a large research domain or in support of societal challenge and EU priorities.
• INFRATECH - Next generation of scientific instrumentation, tools, methods, and advanced digital solutions of research infrastructures and fostering innovation and cocreation with industry, to support research infrastructure needs for technology development to maintain and upgrade their services and to create new ones, and to support the Destination Earth initiative.
• INFRANET - Network connectivity in Research and Education – Enabling collaboration without boundaries, providing high-bandwidth networks and network services to interconnect researchers, data and computing resources in a non-discriminatory way regardless of the location of the users and the resources to allow scientists to conduct excellent research.