This European Commission document reports on the Horizon 2020 Science with and for Society (SwafS) project portfolio results. The objective of this report is to convey the achievements of the SwafS part of Horizon 2020, stemming from funded projects and key activities. Its purpose is to serve as input for the preparation of the Horizon Europe programme implementation. The report covers all thematic areas of Swafs: research ethics and research integrity, science education, science careers, gender equality, institutional changes towards responsible research and innovation, citizen science and citizen engagement, open access and science communication.